Link: Networks of genes behind obesity - Diet and nutrition- msnbc.com.
Even though the whole philosophy of disease-ifying weight continues to bug me, I confess to being intrugued by this kind of research. As I had already started to surmise as just a Scientific American level layperson, this research demonstrates that the body's genetic regulatory systems are not just a simple set of on/off switches, but an incredibly complex system rife with multiple feedback loops, redundancies, and ohter complexities. So when you're talking about the impact of high levels of body fat on overall health, it's only to be expected that there are numerous different command-and-control gene networks involved in mediating that impact. Which would suggest why most current medical solutions for obseity, which typically tend to intervene at just one point in what turns out to be a complex cascade of biochemical events, tend to backfire in all the ways that they do--it's like pulling just one pickup stick out of a whole pile and not anticipating that the rest of the pile won't shift around or even come tumbling down.
As I read between the lines of this article, I also note more evidence for the fact that adipose tissue is not just an inert "container" for body fat, but living tissue like any other bodily tissue, with its own unique genetically-supervised functions, including feedback loops that influence other tissues of the body.
I've also learned, from long experience of reading these kinds of articles in mass media, that things can often get oversimplified. So I went and looked up the abstracts of the original scientific research papers on which this article is based. At least to judge from the abstracts, the NBC article seems to be more-or-less on track--though unfortunately one can't see the full texts without shelling out bucks. But if you want to check out the abstracts, you can go here and here.
Weekly weigh-in: plateau? bottom? And whither this blog?
First, the numbers:
As regular readers of this blog may have noticed, I've been plateaued at 192 pounds for about a month now. You'll also remember that I had vowed I was going to let my weight find its own natural stopping point, without doing any extraordinary alterations to my routine to force my weight lower.
So I'm wondering now: is this it? Have I reached my body's natural preferred stopping point? Not that I'd be changing my current routine one whit, any more than I planned to change it if I weren't at bottom. In fact, this may well be a moot point from a practical standpoint--I've got a healthy routine, it's working for me, so if it ain't broke don't fix it.
It does, however, make me wonder what I should do with this blog from this point forward. After all, it's no more exciting for me to keep entering essentially the same data week after week than it must be for you folks out there to read it! And the truth be known, I pretty much laid out the bulk of my philosophy about healthy weigh management--and vented the bulk of my angst about the dieting industry--in these first two years of blogging.
So I'm considering expanding the focus of this blog, from a personal weight-management journal to a more wide-ranging blog about my interests in food. This would of course still include my weigh management routine--after all, I'm not going to stop any of my disciplines just because I'm changing the blog's focus. And if something should change about my weight management routine, of course you'll hear about it here right off. And I have occasionally mentioned my other food interests here from time to time. I'd just be bringing those other interests more into the foreground.
I'm not sure exactly how and when these changes will start showing up on this blog, but watch this space, and sooner or later all will be revealed.
March 06, 2008 at 04:59 PM in General commentary, Weekly weigh-in | Permalink | Comments (2)